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Home » Programs » 5 Week Programs » Mike Israetel 5 Week Hypertrophy Workout Routine Spreadsheet

Mike Israetel 5 Week Hypertrophy Workout Routine Spreadsheet

By Kyle Risley
Last updated June 29, 2026

Experience level: Advanced, Intermediate

Weeks: 5

Periodization: Linear Periodization, Undulating Periodization

Program goal: Hypertrophy

Uses RPE: Yes

Uses 1RM Percentage(%): Yes


As an affiliate of various sites, including Amazon Associates, I may earn a commission on qualifying purchases via links in this post at no extra cost to you. See Full Disclosure

This is a 6 day hypertrophy program built on Dr. Mike Israetel’s volume landmarks. You start each muscle group near the volume where growth kicks in, add sets and weight every week for four weeks, then take a deload on week 5. The spreadsheet does the bookkeeping, so you can see exactly how many sets each muscle is getting and when to back off.

The whole idea is volume landmarks: the set ranges that maintain muscle (MV), start growing it (MEV), grow it fastest (MAV), and the ceiling your body can still recover from (MRV). Instead of running the same sets every week like a fixed program, you ramp volume across the mesocycle toward your MRV and then reset with a deload. It’s the Renaissance Periodization approach to hypertrophy training, turned into a spreadsheet you can actually run.

I’d point intermediate and advanced lifters here, not beginners. It’s six days a week and a lot of volume to manage, and you get more out of it once you can tell the difference between a productive amount of work and too much. If you’re newer or short on time, start with a simpler program like PHUL and come back to this when you want to push volume on purpose.

Table of Contents

  • 1 Mike Israetel Hypertrophy Video Overview
  • 2 Mike Israetel Hypertrophy on Boostcamp
  • 3 5 Week Hypertrophy Workout Routine Spreadsheet
    • 3.1 Using the Spreadsheet
  • 4 Understanding Hypertrophy Training Volume
  • 5 How to Find Your Individual Optimal Training Volumes for Hypertrophy
    • 5.1 How to Find Your Maintenance Volume
    • 5.2 How to Find Your Minimum Effective Volume
    • 5.3 How to Find Your Maximum Adaptive Volume
  • 6 Mike Israetel Hypertrophy FAQs
    • 6.1 What is the Mike Israetel hypertrophy program?
    • 6.2 Is this program good for beginners?
    • 6.3 What are MEV, MAV, and MRV?
    • 6.4 How long should I run it?
    • 6.5 Can I swap exercises?
    • 6.6 What should I do after this program?

Mike Israetel Hypertrophy Video Overview

Dr. Mike Israetel covers how hypertrophy training should change as you move from beginner to intermediate to advanced in this video.

Beginner, Intermediate and Advanced Hypertrophy Training Differences
Watch this video on YouTube.

Mike Israetel Hypertrophy on Boostcamp

Prefer to track it on your phone? You can run this one free on Boostcamp, which logs your sets and keeps the weekly volume count for you.

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5 Week Hypertrophy Workout Routine Spreadsheet

A terrific Lift Vault reader submitted this spreadsheet to help provide more structure to the recommendations made by Mike Israetel in the article. It makes it much easier to use the workout based on your own current strength levels.

This is a 6 day hypertrophy workout routine that runs for a 4 week mesocycle and includes a deload on week 5.

Using the Spreadsheet

  1. There are some extremely important concepts about hypertrophy explained below. Please read them – or better yet, read Mike Israetel’s article in its entirety.
  2. Adjust your starting weights – use the calculator on the “Week 1” sheet if needed. Be conservative – there is lots of time to add weight and remember this is a hypertrophy program.
  3. The exercises are pulled from the various muscle group articles on Renaissance Periodization.
  4. The number of sets done each week is tracked on the “Sets per Week Summary” tab.
  5. Pro Tip: It’d probably be a good idea to track RPE or RIR for each exercise so you can look back on the mesocycle and see if the number of sets used was effective or not.

Spreadsheet built by a Lift Vault reader, based on Dr. Mike Israetel’s training volume landmarks at Renaissance Periodization.

Dr. Mike Israetel Hypertrophy (Volume Landmarks) | LiftVault.com

Understanding Hypertrophy Training Volume

  • maintenance volume (MV)
    • Maintenance volume is the number of sets needed to maintain your current muscular size.
  • minimum effective volume (MEV)
    • Minimum effective volume is the lowest number of sets needed to increase your muscular size.
  • maximum adaptive volume (MAV)
    • Maximum adaptive volume is the volume range where the most muscular growth occurs.
  • maximum recoverable volume (MRV)
    • Maximum recoverable volume is the upper limit of training volume that the body can still recover from (i.e. repair and grow muscle mass).
    • Regular training in the MRV range will result in excessive accumulated fatigue and will not induce hypertrophy. Limited training near an athlete’s MRV prior to a deload can be effective for achieving super-compensation.

This allowed for a much more finely tuned hypertrophy-based workout depending on the muscle groups the athlete wanted to develop. It also allows for individual differences to be recognized, as different athletes will have different MV, MEV, MAV, and MRV.

It is important for a lifter to begin to identify these variables for themselves through training. If these variables are not currently understood, they can be learned through experimentation and observation.

How to Find Your Individual Optimal Training Volumes for Hypertrophy

Below are summaries of how to find different volume training landmarks for yourself. A full explanation is available in Dr. Israetel’s article.

Many of the below volumes reference “rep strength” or “performance.” Here is how this can be measured.

Performance or rep strength can be measured using RPE or reps in reserve. If during Week 1 of training you did 4 sets of 12 reps of bicep curls with 15 lb dumbbells and felt you had 2 reps in reserve at the end of your 4th set and then you repeated this weight*rep*set scheme at the end of a mesocycle and felt like you had 5 reps in reserve after the final set of curls – congratulations, you increased performance.

Similarly, if the last set during week 1 was RPE 8 and that same weight*rpe*set scheme was an RPE 6 on the test week after a mesocycle, performance was increased.

How to Find Your Maintenance Volume

  • Two to three times per year should be spent doing maintenance training and eating to resensitize your body to stimulus and growth.
  • Start by following the “MV” volume recommendations laid out in the article (also available on the “Sets per Week Summary” tab in the spreadsheet below).
  • If your rep strength has been conserved at the end of one mesocycle at the prescribed volume, then the volume was adequate.
    • Next mesocycle: try reducing the number of sets to see if your MV is even lower.
  • If your rep strength declined, volume was too low and your MV is higher than the volume of work down in the previous mesocycle.
    • Next mesocycle: increase the number of sets and see if rep strength can be conserved.
  • General tip: be conservative. Your MV is probably lower than you think.

How to Find Your Minimum Effective Volume

Mike outlines two methods for calculating your minimum effective volume.

  • Method 1: Start with recommended MEV (again, these are noted in the article as well as in the spreadsheet below on the “Sets per Week Summary” tab) and run for one mesocycle. Increase weights each week, but do not increase the number of sets. Test your performance on core exercises for each muscle group at the end of the mesocycle.
    • If it improved, the volume of the last mesocycle was at or above your MEV. Try lowering volume by 2 sets each week and see if progress can continue to be made. Do this until you discover a volume that does not increase your performance. Add 2 sets to the volume that did not increase your performance and this is your approximate MEV.
    • If your strength on a core exercise for a muscle group did not improve, the volume was below your MEV. Try adding 2 sets per week until performance improves.
  • Method 2: To approximate whether a particular training session was within your MEV, ask the following questions.
    • Did the training session provide a pump?
      • No pump = 0 points
      • Some pump = 1 point
      • Great pump = 2 points
    • Did the training session challenge the target muscles?
      • No = 0 points
      • Lots of tensions and fatigue = 1 point
      • Muscles felt stressed and exhausted near their limit = 2 points
    • Did the training session make you sore?
      • No = 0 points
      • Stiff for a few hours after or a little sore the next day = 1 point
      • Sore for multiple days = 2 points
  • A score between 2 and 4 is likely to be within your MEV.
    • If you’re training a muscle group 2x per week, expect more 4’s.
    • If you’re training a muscle group 3-4x per week, expect more 3’s.
    • If you’re training a muscle group 5-6x per week, expect more 2’s or even 1’s.

How to Find Your Maximum Adaptive Volume

Finding MAV is done by continually adding sets until soreness becomes excessive and performance begins to degrade. Here is how to quantify excessive soreness and degrading performance.

  • Soreness at the end of a session
    • No soreness = 1 point
    • A little stiff or sore afterward, but not sore at all by the time the next session for that muscle group occurred = 2 points
    • Definitely getting DOMS (delayed onset muscle soreness), but it went away just in time for that muscle group’s next session = 3 points
    • You got DOMS and were still feeling them during the next session = 4 points
  • Performance during a session (this is modified from the article in an attempt to make it more usable)
    • You had had 2+ reps in reserve, RPE 7 or lower = 1 point
    • You had 1 rep in reserve, RPE 8 = 2 points
    • You just barely got all the reps, RPE 9/9.5 = 3 points
    • You missed reps or had performance degrade from last week (accounting for different weights, etc.) = 4 points
  • How many sets to add based on points
    • 1 + 1 = add 2 or 3 sets to that exercise
    • Any 2’s = add 1 set to that exercise
    • Any 3’s = do not add any sets to that exercise
    • Any 4’s = consider taking a light session, half week, or full deload

Mike Israetel Hypertrophy FAQs

What is the Mike Israetel hypertrophy program?

It’s a 6 day, 5 week hypertrophy mesocycle based on Dr. Mike Israetel’s volume landmark framework. You train each muscle group in the set range that drives growth, ramp the volume up each week, then deload on week 5 to recover and grow.

Is this program good for beginners?

Not really. The volume is high and it asks you to autoregulate, which is hard to judge when you’re new. A beginner grows fine on far less work. Start on something simpler like PHUL or PHAT, then come here once you have a feel for how much work you actually recover from.

What are MEV, MAV, and MRV?

They’re volume landmarks measured in working sets per muscle per week. MEV is the least volume that still builds muscle, MAV is the range where you grow fastest, and MRV is the most you can recover from before fatigue starts eating your progress. The program walks each muscle up from MEV toward MRV across the mesocycle. The full breakdown is in the sections below.

How long should I run it?

One mesocycle is the 4 build weeks plus the week 5 deload. You can run it back to back, but use the deload and the RPE/RIR notes to decide your starting volume for the next round. If your performance stalled, your sets crept past what you could recover from, so start the next block lower.

Can I swap exercises?

Yes. Swap any exercise for one that trains the same muscle in a similar rep range. Change it on the General Overview tab of the spreadsheet. Just note that the sets and reps don’t update automatically, so adjust those by hand if your swap calls for it.

What should I do after this program?

Run another mesocycle with adjusted volume, or rotate to a different hypertrophy structure for variety. PHAT and PHUL are good changes of pace, and a maintenance block every few mesocycles keeps you fresh for the next hard push.

About Kyle Risley

Kyle Risley founded Lift Vault in 2016 to make finding great powerlifting programs easier. Since then, the site has grown to include hundreds of programs for strength, bodybuilding, Olympic weightlifting, and more. He currently lives in Massachusetts and continues to compete in powerlifting.

Filed Under: 5 Week Programs, Bodybuilding Program, Programs
Tagged With: 5 Week Workout Plan, 6 Day Bodybuilding Program, 6 Day Workout Plan
Squat frequency: 2
Bench press frequency: 2
Deadlift frequency: 1

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